Cancer stem cells 翻译

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August undefined, 2024

WebFeb 15, 2024 · Abstract. Cancer stem cells (CSCs) are an uncommon subset of tumor cells capable of self-renewal, differentiating, and recreating the parental tumor when transplanted into the murine background ... WebApr 14, 2024 · In this study, we found that a specific Menin-MLL1 inhibitor, MI-503 inhibits neuroblastoma cancer stem cells (NB CSCs; CD114+ cells) to inhibit overall neuroblastoma (NB) growth in both in vitro and in vivo NB tumor models. NB is an extracranial solid pediatric cancer that accounts for about 15% of all pediatric cancer …

Cancer Stem Cells NEJM

WebCancer stem cells (CSCs) are a small subpopulation of self-renewing malignant and oncogenic cells that drive tumor initiation and progression. CSCs play pivotal roles in tumor initiation, progression, cell death resistance, therapy resistance, and tumor recurrence following treatment and remission. Exposure to chemo- or radiotherapy may also ... WebMar 19, 2024 · In stem cell transplants, stem cells replace cells damaged by chemotherapy or disease or serve as a way for the donor's immune system to fight some types of cancer and blood-related diseases, such … poor collaboration in healthcare

Cancer stem cells as key drivers of tumour progression

WebMar 6, 2024 · Cancer stem cells (CSCs) are subpopulations of cancer cells sharing similar characteristics as normal stem or progenitor cells such as self-renewal ability and multi-lineage differentiation to drive tumour growth and heterogeneity. Throughout the cancer progression, CSC can further be induced from differentiated cancer cells via the … WebJul 20, 2024 · A bone marrow transplant may be used to: Safely allow treatment with high doses of chemotherapy or radiation by replacing or rescuing the bone marrow damaged by the treatment. Replace bone marrow that's not working properly with new stem cells. Provide new stem cells, which can help kill cancer cells directly. WebIn Stem Cells (Second Edition), 2014. 12.2 Introduction to Stem Cells and Cancer. Although the idea that cancer stem cells exist and are essential contributors to aggressive cancer growth dates far back into the last century, the question of the identity of these cells has proven extremely difficult to answer. Only recently has the concept gained wider … shareholder value maximization theory

Cancer Stem Cells and Self-renewal Clinical Cancer …

WebChronic GVHD can start anywhere from about 90 to 600 days after the stem cell transplant. A rash on the palms of the hands or the soles of the feet is often the earliest sign. The rash can spread and is usually itchy and dry. In severe cases, the skin may blister and peel, like a bad sunburn. A fever may also develop. WebIn Stem Cells (Second Edition), 2014. 12.2.1 A Brief History of Cancer Stem Cells. First indications that cancer stem cells may exist emerged at the end of the twentieth century at about the same time embryonic stem cells were discovered in mice. The idea evolved from research carried out to explain the cause of a relatively common form of blood cell … shareholder value \u0026 investor relationsWebCancer Stem Cells. The stem cell theory of cancer proposes that among the many different types of cells within a cancer, there exists a subpopulation of cells called cancer stem cells that multiply indefinitely, are resistant to chemotherapy, and are thought to be responsible for relapse after therapy. Cancer stem cells also give rise to highly ... shareholder value maximization

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Cancer stem cells 翻译

Web我一直觉得，干细胞龛（Stem Cell Niche）这个翻译怪怪的，毕竟读书少的我一度把龛读成long...我觉得，更贴切更信达雅的翻译明明应该是干细胞老巢，或者干细胞小窝窝？. Anyway，Stem Cell Niche, 说的就是干细胞的 … WebDec 7, 2011 · Infiltrating tumour cells need to induce stromal POSTN expression in the secondary target organ (in this case lung) to initiate colonization. POSTN is required to allow cancer stem cell ...

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WebStem cell transplants are procedures that restore blood-forming stem cells in people who have had theirs destroyed by the high doses of chemotherapy or radiation therapy that are used to treat certain cancers. Blood-forming … WebJun 22, 2016 · Abstract. Heterogeneity within and between tumors is a well-known phenomenon that greatly complicates the diagnosis and treatment of cancer. A large body of research indicates that heterogeneity develops …

WebStem cells are key to our normal development and health from conception through adulthood. Embryonic stem cells produce the progenitors and patterns that determine how our organs, muscles, sinews, and skeletons … WebApr 6, 2024 · Cancer stem cells are rare immortal cells within a tumour that can both self-renew by dividing and give rise to many cell types that constitute the tumour, and can therefore form tumours. Such ...

WebApr 12, 2024 · 中山教授表示：“这项研究成果为癌症治疗提供了新的靶点。我们可以通过抑制p57的活性，唤醒癌干细胞活动，从而使抗癌药物发挥作用。目前正在推进开发基于这一思路的药物。”该研究成果已发表在《Cancer Research》杂志上。 WebJan 8, 2024 · AML is a type of cancer that goes by several other names, such as acute myelocytic leukemia, acute myelogenous leukemia, acute granulocytic leukemia, or acute non-lymphocytic leukemia. It is most common in people who are older. AML happens when blasts don't mature and build up in your bone marrow. When the production of these …

WebSep 18, 2013 · The cancer stem-cell model provides one explanation for the phenotypic and functional heterogeneity among cancer cells in some tumours 1, 2, 3, 4, 5. The model posits that some cancers...

WebJul 1, 2024 · Recent efforts in cancer stem cell (CSC) biology suggest that a subpopulation of tumor-initiating cells within the tumor bulk represents the root of tumor recurrence and therapy resistance. In recent years, metabolic phenotype of CSCs of various tumor types has been identified. This breakthrough has shed light on the underlying mechanism by ... shareholder value analysis slowcatWebHigh recurrence rates and poor survival rates of metastatic bladder cancer emphasize the need for a drug that can prevent and/or treat bladder cancer progressi. 掌桥科研一站式科研服务平台. 学术工具. 文档翻译; shareholder value investor relationsWebRecent efforts in cancer stem cell (CSC) biology suggest that a subpopulation of tumor-initiating cells within the tumor bulk represents the root of tumor recurrence and therapy resistance. In recent years, metabolic phenotype of … shareholder value creation definitionWebJun 14, 2010 · Abstract. The cancer stem cell (CSC) or cancer-initiating cancer (C-IC) model has garnered considerable attention over the past several years since Dick and colleagues published a seminal report … shareholder vs beneficial ownerWebChronic GVHD can start anywhere from about 90 to 600 days after the stem cell transplant. A rash on the palms of the hands or the soles of the feet is often the earliest sign. The rash can spread and is usually itchy and dry. In severe cases, the skin may blister and peel, like a bad sunburn. A fever may also develop. poor cold fred advertCancer stem cells (CSCs) are cancer cells (found within tumors or hematological cancers) that possess characteristics associated with normal stem cells, specifically the ability to give rise to all cell types found in a particular cancer sample. CSCs are therefore tumorigenic (tumor-forming), perhaps in contrast to other non-tumorigenic cancer cells. CSCs may generate tumors through the s… shareholder voting proxy formWebMar 13, 2024 · In certain multicellular organisms, stem cells can serve as reservoir of cells to produce, maintain, repair or even regenerate many tissues. Similarly, in cancer, a distinct fraction of cells, called cancer stem cells, may fuel the entire tumor as the disease emerges and progresses (Batlle and Clevers, 2024).How to define, isolate or … poor college life hacks